The liver is the central organ for carbohydrate metabolism to maintain the blood glucose concentration within a normal range. Glucose breakdown or synthesis in the liver is tightly regulated by insuli

DataCite Commons2022-01-12 更新60

Insulin-administrated phosphorylation of the CNS proteins in Lymnaea

神经细胞蛋白质组学

胰岛素信号通路

In the gastropod mollusc Lymnaea stagnalis, insulin-like peptides in the central nervous system (CNS) control behavioral changes associated with an associative learning. We examined the responding mol

NIAID Data Ecosystem30

Feedback Inhibition of CREB Signaling Promotes Beta Cell Dysfunction in Insulin Resistance.

细胞功能障碍

胰岛素信号通路

Although persistent elevations in circulating glucose concentrations promote compensatory increases in pancreatic islet mass, unremitting insulin resistance causes a deterioration in beta cell functio

NIAID Data Ecosystem70

Analysis of C. elegans DAF-16 phosphorylation in different genetic backgrounds.

胰岛素信号通路

蛋白质磷酸化

C. elegans DAF-16/FOXO phosphorylation in different genetic backgrounds was analyzed by mass spectrometry of affinity purified HA-tagged DAF-16. Genetic backgrounds studied include par-1 hypomorphic m

NIAID Data Ecosystem40

Bistable insulin response: the win-win solution for glycemic control

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