HCMI Searchable Catalog

HCMI Searchable Catalog is a continuously updated resource for querying the available next-generation models developed by the Human Cancer Models Initiative (HCMI). Within the Catalog, users can search by patient demographics, tumor, and model elements including age at diagnosis, sex, treatment information, clinical tumor diagnosis, primary site, clinical stage, and type of model (e.g. 3D-organoid, 2D-conditionally reprogrammed cells), open-access masked somatic MAF variants, etc.

HCMI可检索目录是由人类癌症模型倡议（Human Cancer Models Initiative, HCMI）开发的持续更新型检索资源，用于查询该倡议研发的可用下一代模型。在该目录中，用户可基于患者人口统计学特征、肿瘤相关特征及模型要素开展检索，涵盖确诊年龄、性别、治疗信息、临床肿瘤诊断结果、原发部位、临床分期，以及模型类型（如三维类器官（3D-organoid）、二维条件重编程细胞（2D-conditionally reprogrammed cells））、开放获取的掩码体细胞突变等位基因频率（MAF）变异数据等。

搜集汇总

背景与挑战

背景概述

HCMI Searchable Catalog是Human Cancer Models Initiative（HCMI）项目提供的一个可搜索资源，用于查询患者来源的下一代癌症模型。该目录允许用户根据患者人口统计学、肿瘤特征和模型类型进行检索，并可通过NCI的Genomic Data Commons访问相关临床和分子数据。