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A CRISPR/Cas9 knock-out screen reveals NF-κB suppressors that regulate peptide/MHC-1 display in neuroblastoma tumors

NIAID Data Ecosystem2026-03-10 收录

肿瘤免疫逃逸

CRISPRi筛选

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA471778 数据链接链接失效反馈

官方服务：

资源简介：

Dataset CRIPSR screens from Spel et al. 2018

应用场景：

创建时间：

2018-05-17

白血病发病机制

CRISPRi筛选

Investigating Bcor target genes in BcorΔE9-10KrasG12D leukaemia with a custom CRISPR dropout screen BcorΔE9-10KrasG12D cell line was transduced with a custom CRISPR library and a dropout screen was pe

NIAID Data Ecosystem30

Essential gene profiles for human pluripotent stem cells identify uncharacterized genes and substrate dependencies. Mair et al.

干细胞鉴定

CRISPRi筛选

Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding pluripotency and lineage differentiation mechanisms,

NIAID Data Ecosystem20

RNA-sequencing and CRISPR/Cas9 Screen of PEO1 cells grown in suspension.

CRISPRi筛选

失巢凋亡逃逸

RNA-sequencing of PEO1 cells grown in suspension (SUS1 and SUS3) was performed to evaluate transcriptional reprogramming during anokis escape. CRISPR/Cas9 screen of PEO1 cells grown in adherent and su

NIAID Data Ecosystem00

Mitochondrial and ER membrane protein trafficking CRISPR screens

线粒体/内质网蛋白运输

CRISPRi筛选

The trafficking of specific protein cohorts to the correct subcellular location at the correct time is essential for every signaling and regulatory process in biology. Gene perturbation screens could

NIAID Data Ecosystem30

Genome-wide CRISPR screen of post-transcriptional regulators of IL6 3'UTR

CRISPRi筛选

IL6转录后调控

The aim of this research is to uncover novel post-transcriptional mechanisms regulating IL6 3'UTR. IL6 is one of the most essential cytokines and its expression is tightly controlled during acute and

NIAID Data Ecosystem10

A CRISPR/Cas9 knock-out screen reveals NF-κB suppressors that regulate peptide/MHC-1 display in neuroblastoma tumors

资源简介：

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