Additional file 1: of The intolerance to functional genetic variation of protein domains predicts the localization of pathogenic mutations within genes

A text file in BED format containing domain subRVIS sub-region boundaries. Each sub-region name contains three fields separated by a colon - the gene name; the domain type, which is either the CDD PSSM-Id of the aligned domain or a â -â denoting that no CDD domain was aligned to this region; the domain type again followed by an underscore, followed by the occurrence number of this domain type. (TXT 10178 kb)一份采用BED格式的文本文件，包含subRVIS结构域（domain）亚区域的边界信息。每个亚区域的名称由三个以冒号分隔的字段构成：第一字段为基因名称；第二字段为结构域类型，其取值包含两种类型：一是比对得到的结构域对应的保守结构域数据库（Conserved Domain Database，CDD）位置特异性得分矩阵（Position-Specific Scoring Matrix，PSSM）编号，二是用于表示该区域未比对到任何CDD结构域的标记；第三字段为结构域类型本身，其后跟随下划线，再紧跟该结构域类型的出现序号。（文本文件，大小10178 KB）