Modular microenvironment components reproduce vascular dynamics de novo in a multi-scale agent-based model: VASCULAR FUNCTION

Data and results for `VASCULAR FUNCTION` simulations.

Simulations of cancerous cells in colony and tissue contexts with pattern and various graph layouts with degradation by cancerous cells and vascular remodeling. Each condition is run for 15 days (21600 ticks) with 10 replicates (random seeds 0 - 9).
Cancerous cells (max_height x 1.5, meta_pref x 1.5, migra_threshold x 0.5) are introduced to the center of the environment after a 1 day delay. Snapshots are taken every 0.5 days (720 ticks). The data folder contains .tar.xz compressed replicate sets.
The data.graph folder contains .tar.xz compressed replicate sets for .GRAPH output. The results folder contains .pkl files of data parsed into arrays. Simulations are labeled as: [context]_[sites]_[layout]

- [context]
- C = colony context, cancerous cells only
- CH = tissue context, cancerous cells and healthy cells
- [sites]
- PATTERN = site architecture defined by pattern
- GRAPH = site architecture defined by graph layout
- [layout]
- simulations with PATTERN do not have a layout label
- Lav = line root graph with one artery and one vein (L11)
- Lava = line root graph with two arteries and one vein (L21)
- Lvav = line root graph with one artery and two veins (L12)
- Sav = single root graph with one artery and one vein (S11)
- Savav = single root graph with two arteries and two veins (S22)

血管功能模拟数据与结果。
模拟癌变细胞在群落和组织环境中的生长，以及不同图案和图形布局下的癌变细胞降解与血管重塑。每个条件均运行15天（21600次迭代），进行10次重复实验（随机种子0-9）。在延迟1天后，将癌变细胞（最大高度x1.5，元偏好x1.5，迁移阈值x0.5）引入环境中心。每隔0.5天（720次迭代）进行一次快照。数据文件夹包含.tar.xz压缩的重复集。
数据.graph文件夹包含.tar.xz压缩的重复集，用于.GRAPH输出。结果文件夹包含解析为数组的.pkl文件。模拟以[情境]_[位置]_[布局]进行标记。

- [情境]
- C = 群落环境，仅含癌变细胞
- CH = 组织环境，含癌变细胞和健康细胞
- [位置]
- PATTERN = 由图案定义的场所结构
- GRAPH = 由图形布局定义的场所结构
- [布局]
- 采用PATTERN的模拟无需布局标签
- Lav = 具有一条动脉和一条静脉的线根图（L11）
- Lava = 具有两条动脉和一条静脉的线根图（L21）
- Lvav = 具有一条动脉和两条静脉的线根图（L12）
- Sav = 具有一条动脉和一条静脉的单根图（S11）
- Savav = 具有两条动脉和两条静脉的单根图（S22）