Three-dimensional analysis of genome organization in CTCF-WT and CTCF-KO dendritic cells (HiChIP II)
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE215044
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资源简介：
Purpose: The goals of this study are to analyze global transcriptional, epigenetic and topological changes in dendritic cells under LPS treatment condition and to investigate how CTCF regulates three-dimensional chromatin interaction in inflammatory response. Conclusions: Our study provides the detailed analysis of transcriptional, epigenetic and topological genome profiles in mouse dendritic cells under LPS treatment condition. Moreover, our data show how three-dimensional enhancer networks control gene expression during DC activation. NF-κB inhibitor (JSH23) and LPS treated HiChIP profiles of CTCF-WT cells with biological replicates.
创建时间：
2023-03-14
