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JMJD1A inhibits proliferation and aggressiveness of gastric cancer by up-regulating RUNX3

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP248223
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资源简介:
The histone demethylase JMJD1A(Jumoji domain containing 1A) is overexpressed in multiple cancers and promotes cancer progression. However, the role and mechanism of JMJD1A in gastric cancer remains poorly understood.Here, we found that JMJD1A could suppress gastric cancer cell proliferation, migration, invasion and xenograft tumor growth. Using RNA sequencing, we identified RUNX3 as a novel target gene of JMJD1A. Overall design: Examination the total RNA change of JMJD1A depletion in SGC-7901 cells
创建时间:
2020-10-19
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