miRNAs expression changes in translocation t(8;21)- and t(15;17)-positive as well as MLL- rearranged pediatric AML patients.

miRNAs distinguishing the two translocations from themselves or all other cytogenetic subtypes as well as miRNAs differentially expressed in MLL-rearranged samples compared to all other cytogenetic subtypes. Shown are those with at least 1.8-fold expression change (as indicated by the arrows) in a minimum of one comparison and fold changes of the comparisons are given. Mann-Whitney-U (MWU) statistical testing was performed for this comparison as indicated. Levels: p<0.05 = *; p<0.01 = **. miRNAs defined as class identifiers for the three cytogenetic aberrations using either patient samples of all cytogenetic subtypes (#) or the t(8;21)-, t(15;17)- or MLL-rearranged subtypes alone (§) using PAM are indicated as well.