Long-term stability of 10mg/mL dobutamine injectable solutions Dataset

This dataset describes the raw and analyzed data of a stability study whose aim was to compare the stability of 10mg/mL ready-to-use dobutamine solutions when stored in either polypropylene syringes or cyclic-oleofin copolymer vials, diluted either in dextrose 5% in water or normal saline solution and stored in a dark enclosure at either frozen (-20±5°C), refrigerated (+5±3°C) or ambient temperatures (+25±2°C with 60±5% relative humidity for 12 months. Calibration solutions were prepared by diluting stock solutions with dextrose 5% in water (D5W) or normal saline solution (NS) to obtain eight different standard levels: 0.5, 0.6, 0.7, 0.8, 0.9, 1, 1.3, 1.5 mg/mL (n=6)本数据集收录了一项稳定性研究的原始数据与分析结果，该研究旨在对比10mg/mL即用型多巴酚丁胺溶液（dobutamine solutions）的稳定性。受试溶液分别以聚丙烯注射器（polypropylene syringes）或环烯烃共聚物小瓶（cyclic-oleofin copolymer vials）包装，采用5%葡萄糖水溶液（dextrose 5% in water, D5W）或生理盐水（normal saline solution, NS）稀释后，置于避光环境中分别于冷冻(-20±5℃)、冷藏(+5±3℃) 或室温(+25±2℃，相对湿度60±5%)条件下储存12个月。 校准溶液的制备方式为：以D5W或NS稀释储备溶液，配制得到8种不同标准浓度梯度：0.5、0.6、0.7、0.8、0.9、1、1.3、1.5 mg/mL，每组设置6个平行样本（n=6）。