Crystal structure of human Pim-1 kinase in complex with a consensus peptide and fragment like molecule 3,4-Dibromothiophene-2-carboxylic acid

Crystal structure of human Pim-1 kinase in complex with a consensus peptide and fragment like molecule 3,4-Dibromothiophene-2-carboxylic acid Descriptor: 3,4-bis(bromanyl)thiophene-2-carboxylic acid, Pimtide, Serine/threonine-protein kinase pim-1 Authors: Siefker, C, Heine, A, Klebe, G. Deposit date: 2017-02-11 Release date: 2018-02-28 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.118 Å) Cite: A crystallographic fragment study with human Pim-1 kinase to be published

人类Pim-1激酶与共有肽段及类片段分子3,4-二溴噻吩-2-羧酸的共晶结构。描述符：3,4-二溴噻吩-2-羧酸（3,4-bis(bromanyl)thiophene-2-carboxylic acid）、Pimtide、丝氨酸/苏氨酸蛋白激酶Pim-1（Serine/threonine-protein kinase pim-1）；作者：Siefker C、Heine A、Klebe G；提交日期：2017年2月11日；发布日期：2018年2月28日；最后修改日期：2024年10月23日；实验方法：X射线衍射（分辨率2.118埃）；引用：一项针对人类Pim-1激酶的晶体学片段研究，即将发表。