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Genome-scale CRISPR knockout screen for Pteropine Orthoreovirus PRV3M

ChEBI2025-12-31 更新2026-07-12 收录

病毒宿主因子筛选

CRISPRi功能基因组学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-14485 数据链接链接失效反馈

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资源简介：

Genome-scale CRISPR knockout screen for Pteropine Orthoreovirus PRV3M

应用场景：

创建时间：

2025-12-31

癌症药物机制研究

CRISPRi功能基因组学

BT20 (TNBC) cells were cultured with either DMSO (v/v%) or Erlotinib (10uM) for 24 hours to observe differential expression changes between conditions. CAS-9 expressing BT20 (TNBC) cells were transduc

NIAID Data Ecosystem50

List of guideRNAs used for validation.

病毒宿主因子筛选

CRISPR功能分析

While SARS-CoV-2 primarily infects the respiratory tract, clinical evidence indicates that cells from diverse cell types and organs are also susceptible to infection. Using the CRISPR activation (CRIS

Figshare2025-07-17 更新20

Effect of CRISPR activation of Zbtb7b, Vps72, Gba, or Mrpl9 in liver tumorigenesis in mice

癌症驱动基因

CRISPRi功能基因组学

Hepatocellular carcinomas (HCCs) undergo chromosomal amplifications with resultant increases in gene expression levels, yet the impact of these changes remains largely unknown. We sought to identify c

NIAID Data Ecosystem00

Additional file 1 of CoRe: a robustly benchmarked R package for identifying core-fitness genes in genome-wide pooled CRISPR-Cas9 screens

CRISPRi功能基因组学

基因必要性筛选

Additional File 1: Table S1. All compared sets of core-fitness and common-essential genes with annotations.

Figshare2021-11-17 更新50

Differential gene expression (FDR 0.05) for CRISPR edited clones.

CRISPRi功能基因组学

免疫应答分析

hTLR4 Cells were transfected a CRISPR/Cas9 construct and a gRNA specific for the rs17622517 locus. Wild type, heterozygous or homozygous clones were isolated and then treated with no LPS, LPS for 90 m

Figshare2021-07-27 更新10

Genome-scale CRISPR knockout screen for Pteropine Orthoreovirus PRV3M

资源简介：

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