Copper metabolism

This pathway shows copper metabolism and translocation for two cell types (enterocytes and hepatocytes), as well as associated disorders for transportation of copper to vesicles. Copper is an essential trace element required for the functioning of metalloenzymes. Copper is ingested through diet, absorbed by enterocytes in the intestinal walls, and sent to hepatocytes via the hepatic portal system. This pathway model was constructed using chapter 39 of the book "Physician's Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases (first edition)" by Blau (ISBN 3642403360)

本路径图展示了两种细胞类型（肠上皮细胞和肝细胞）中的铜代谢与转运过程，以及与铜向囊泡运输相关的疾病。铜作为一种必需的微量元素，对于金属酶的功能至关重要。铜通过饮食摄入，由肠上皮细胞在肠道壁吸收，并通过肝门静脉系统输送到肝细胞。该路径模型系基于Blau所著《遗传代谢疾病诊断、治疗及随访医师指南》（第一版，ISBN 3642403360）的第39章构建。