Prevalence and clinical significance of granulomas in Crohn's disease anal fistula

This study aims to evaluate the prevalence of non-caseating granulomas in the anal fistula tissues of patients with Crohn's disease anal fistula and to explore the correlation between the presence of granulomas and disease severity as well as the need for surgical reoperation. The results showed that the granulomas can serve as valuable histological markers for indicating more severe disease and predicting reoperation.