Comparative study of gene expression in Aspergillus niger solid and submerged growth during sugar beet pulp utilization

In this study, we compared the gene expression pattern of A. niger grown in liquid sugar beet pulp (SBP) at different time points, a by-product of the sugar industry that consists mainly of cellulose, xyloglucan, and pectin. Finally, we compared A. niger genetic response to liquid SBP to that of the same fungus when grown on solid SBP plates and polygalacturonic acid (PGA). In this study, we aimed to reveal the extent to which A. niger response is comparable when grown on solid and submerged cultures. For this, we first studied the gene expression pattern of A. niger grown in liquid sugar beet pulp (SBP) at different time points, a by-product of the sugar industry that consists mainly of cellulose, xyloglucan, and pectin. Finally, we compared A. niger genetic response to liquid SBP to that of the same fungus when grown on PGA and solid SBP plates (previously deposited with GEO accession GSE66641). Part of PGA and liquid SBP datasets were previously deposited with GEO accession GSE98572 (with Sample ID GSM2600976, GSM2600977,GSM2600984, GSM2600985).