Chronic obstructive pulmonary disease (COPD) is characterized by lung parenchymal destruction and small airway remodeling, involving processes like inflammation, cell apoptosis, epithelial-mesenchymal

NIAID Data Ecosystem10

Gene Expression data from the dentate gyrus of the defeated and control mice. Gene Expression data from the dentate gyrus of the defeated and control mice

表观遗传学

circRNA-miRNA-mRNA调控网络

Using various animal models, epigenetic mechanisms have been shown to be mediating the negative effects of chronic stressful events on the progression of depression and other neuropsychiatric disorder

NIAID Data Ecosystem50

Comparative analysis of human and mouse ovaries across age, DOI: 10.1126/science.adx0659, Seurat Object of subsetted C57BL/6 Mouse Oocytes from this study (GSE290742) merged with those from Isola et al. 2024 (https://doi.org/10.1038/s43587-023-00552-5, GEO GSE232309)

生殖生物学

卵巢衰老

The mouse is a tractable model for human ovarian biology, however its utility is limited by incomplete understanding of how transcription and signaling differ interspecifically and with age. We compar

DataCite Commons2025-11-24 更新10

Comprehensive analysis of miRNA-mRNA interactions in ovaries of aged mice

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