Summary of reasons for screen-outs and exclusion from analysis by site.

Percentages shown as a proportion of either total screened (above), or total enrolled (below)* Volunteers may be excluded for multiple reasons therefore columns may sum to >100%** Systolic blood pressure >140 mm Hg and/or diastolic blood pressure >90 mm Hg*** Including headaches, cough, fever, suspected and confirmed malaria**** Active STI, including candidiasis, one possible HSV-1 infection, lower abdominal pain in women, and Bartholin's abscess‡Including suspected and confirmed TB, pneumonia†Includes 125/184 (67.9%) medical exclusions not linked to infectious disease (e.g., trauma, diabetes, cancer)§Includes 4/17 (23.5%) medical exclusions not linked to infectious disease (3 peripheral neuropathy and 1 inebriation at time of visit)