Tumor specific mutations.
收藏Figshare2019-04-23 更新2026-04-29 收录
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Mutations in four genes (Hsp90ab1, Rhoa, Ccnb3, Pdzrn4) showing changes from the reference sequence and not detected in constitutional DNA or in heterozygous (Roquinsan/+) mice or wild-type littermates. Lymphomas from two mice (5293 and 5301) were sequenced. Both tumors showed mutations in Hsp90ab1, Ccnb3 and Pdzrn4 with identical mutations being found in Ccnb3 and Pdzrn4 in the two tumors. 5293 showed a mutation in Rhoa. The nucleotide and amino acid changes are indicated together with the respective variant allele frequency (VAF).
创建时间：
2019-04-23
