Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound Baloxavir

Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound Baloxavir Descriptor: Baloxavir acid, FORMIC ACID, GLYCEROL, ... Authors: Feracci, M, Hernandez, S, Vincentelli, R, Ferron, F, Reguera, J, Canard, B, Alvarez, K. Deposit date: 2021-09-01 Release date: 2022-09-14 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.64 Å) Cite: Biophysical and structural study of La Crosse virus endonuclease inhibition for the development of new antiviral options. Iucrj, 11, 2024与巴洛沙韦（Baloxavir）结合的拉克罗斯病毒L蛋白N端核酸酶结构域晶体结构。配体描述：巴洛沙韦酸、甲酸、甘油……作者：Feracci, M、Hernandez, S、Vincentelli, R、Ferron, F、Reguera, J、Canard, B、Alvarez, K。存入日期：2021-09-01；发布日期：2022-09-14；最后修改日期：2024-11-20。实验方法：X射线衍射（分辨率2.64埃）。引用文献：《用于开发新型抗病毒候选药物的拉克罗斯病毒核酸酶抑制生物物理与结构研究》，Iucrj，第11卷，2024年。