NRF2 activator-treated human cardiac spheres have enhanced maturation and enable disease modeling
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https://www.ncbi.nlm.nih.gov/sra/SRP378754
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资源简介：
To investigate the functions of NRF2 activation on maturation of hiPSC derived cardiomyocytes, we treated 3D hiPSC derived cardiomyocytes with NRF2 activator CDDO-Me at 0.5 µM for 10 days. Transcriptomic analyse was performed to identify molecular actions of NRF2 activation. Overall design: RNA-sequencing analysis was performed to compare global gene expression profiles of hiPSC derived cardiomyocytes treated with NRF2 activator CDDO-Me at 0.5 µM (CDDO-Me) vs. DMSO treatment (DMSO) vs. left ventricle tissue samples (LV).
创建时间：
2022-06-08
