Type I error rates for HIPO observed in datasets simulated under covariance structure estimated from studies of blood lipids.
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See S1 Table 1a and 1b for detailed settings. Summary-level association statistics are simulated for 4 traits using genetic and phenotypic covariance matrices estimated from Global Lipids Genetics Consortium (GLGC) data, with and without population stratification. The results for HIPO-D1 and the most heritable trait are listed. Reported are the average of genome-wide type I error rates across 100 simulations, under significance thresholds p
创建时间：
2018-10-17
