Cryo-EM structure of the partial agonist salbutamol-bound beta2 adrenergic receptor-Gs protein complex.

Cryo-EM structure of the partial agonist salbutamol-bound beta2 adrenergic receptor-Gs protein complex. Descriptor: Beta-2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Yang, F, Ling, S.L, Zhou, Y.X, Zhang, Y.N, Lv, P, Liu, S.L, Fang, W, Sun, W.J, Hu, L.Y.A. Deposit date: 2020-11-15 Release date: 2020-12-16 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.26 Å) Cite: Different Conformational Responses of the beta2-Adrenergic Receptor-Gs Complex upon Binding of the Partial Agonist Salbutamol or the Full Agonist Isoprenaline Natl Sci Rev, 2020部分激动剂沙丁胺醇结合的β2肾上腺素能受体-Gs蛋白复合物的冷冻电镜（Cryo-EM）结构。 描述项：β2肾上腺素能受体、鸟苷酸结合蛋白G(I)/G(S)/G(O)亚基γ2、鸟苷酸结合蛋白G(I)/G(S)/G(T)亚基β1…… 作者：Yang, F、Ling, S.L、Zhou, Y.X、Zhang, Y.N、Lv, P、Liu, S.L、Fang, W、Sun, W.J、Hu, L.Y.A. 提交日期：2020-11-15 发布日期：2020-12-16 最后修改日期：2024-10-23 方法：电子显微镜（分辨率3.26埃） 引用文献：《β2肾上腺素能受体-Gs复合物结合部分激动剂沙丁胺醇或完全激动剂异丙肾上腺素后的不同构象响应》，《国家科学评论》，2020年