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RNA-seq analysis of HK2 under hypoxic condition with Dznep.

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下载链接:
https://www.ncbi.nlm.nih.gov/sra/DRP004445
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资源简介:
Hypoxia plays important roles in progression of chronic kidney diseases. HIF1 (hypoxia inducible factor 1) is a master transcriptional factor under hypoxic condition. To clarify the molecular mechanisms of HIF1 and identify novel lincRNAs under hypoxia, we performed RNA-seq using human renal proximal tubular cells (HK2: human kidney-2). In addition, we use Dznep which is an inhibitor of H3K27me3 to examine the relationship between HIF1 and epigenetic modifiers under hypoxia.
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2018-09-06
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