File S1 - MDR-ER: Balancing Functions for Adjusting the Ratio in Risk Classes and Classification Errors for Imbalanced Cases and Controls Using Multifactor-Dimensionality Reduction

Supporting file containing the following: Example. The computational details of a different factor combination: SNPs(40, 56), and compare the difference between MDR-E and MDR-ER. Figure S1. Sample distributions in the SNPs(40, 56). Figure S2. The ratio between cases and controls in each cell. (A) Results using equation 1 (MDR-E); (B) Results using equation 2 (MDR-ER). Figure S3. Classification results. (A) Classified results of MDR-E; (B) Classified results of MDR-ER. Figure S4. Total number of high- and low-risk among the cases and controls. (A) results of MDR-E;(B) results of MDR-ER. Table S1 Computation of all genotype combinations in SNPs(40, 56). Table S2 Analysis results of the chronic dialysis data sets in 1∶1 cases and controls. Table S3 Analysis results of the chronic dialysis data sets in 1∶2 cases and controls. Table S4. Analysis results of the chronic dialysis data sets in 1∶3 cases and controls. (DOC)