Data_A comparative analysis of mutated genes that are enriched in deceased patients from cBioPortal analysis.xlsx

The cBioPortal for Cancer Genomics was utilized as the primary database to collect patient data and analyze survival outcomes. A total of 16 studies were organized, focusing on clinical data related to patient survival: Brain Lower Grade Glioma (TCGA, Firehose Legacy), Brain Lower Grade Glioma (TCGA, PanCancer Atlas), Diffuse Glioma (GLASS Consortium), Diffuse Glioma (GLASS Consortium, Nature 2019), Diffuse Glioma (MSK, Clin Cancer Res 2024), Glioma (MSK, Clin Cancer Res 2019), Glioma (MSK, Nature 2019), Low-Grade Gliomas (UCSF, Science 2014), Merged Cohort of LGG and GBM (TCGA, Cell 2016), Brain Tumor PDXs (Mayo Clinic, Clin Cancer Res 2020), Glioblastoma (CPTAC, Cell 2021), Glioblastoma (Columbia, Nat Med. 2019), Glioblastoma (TCGA, Cell 2013), Glioblastoma (TCGA, Nature 2008), Glioblastoma Multiforme (TCGA, Firehose Legacy), Glioblastoma Multiforme (TCGA, PanCancer Atlas).  The clinical tab was selected for analysis, and survival graphs were generated for patient groups based on survival status (live and deceased groups). The p-values associated with the survival curves were carefully evaluated to ensure the best accuracy. This study's survival data encompassed 2,444 patients in the living group and 3,226 patients in the deceased group.