Variable transmission of [<i>PSI</i><sup>+</sup>E9]E9 isolates A, F, and G to polymorphs Sup35ref, Sup35E9, and Sup35Δ19 shows that they are distinct prion variants.
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Three prion isolates (A, F, G) in strain 4828 expressing the E9 polymorph of Sup35 were used as cytoduction donors to strain 4830 expressing the different polymorphs. Bold figures show which cytoductants were used as donors in Table 2. The proportions of transmission by variant E9A and E9G to the reference sequence differs from the proportion observed for variant E9F (*) with p<10−10, calculated as described in Methods.
创建时间：
2013-01-31
