Epigenome-wide association study in peripheral white blood cells: Methyl Epigenome Network Association (MENA) project. Epigenome-wide association study in peripheral white blood cells: Methyl Epigenome Network Association (MENA) project

Genome wide DNA methylation from peripheral white blood cells (PWBCs) from individuals from different cohorts included in the MENA project. Samples included 474 individuals (DiOGenes-UNAV n=52, OBEPALIP n=29, Food4Me-UNAV n=39, GEDYMET n=57, ICTUS n=7, NUGENOB-UNAV n=22, PREDIMED-UNAV n=116, RESMENA n=44, OBEKIT n=96, and NormoP n=12). The Illumina Infinium 450k Human DNA methylation Beadchip or Infinium MethylationEPIC Beadchip (for OBEKIT) was used to obtain DNA methylation profiles across approximately 450,000 CpGs in these samples. Overall design: Bisulphite converted DNA from 474 samples from different cohorts were hybridised to the Illumina Infinium 450k Human Methylation Beadchip (DiOGenes-UNAV, OBEPALIP, Food4Me-UNAV, GEDYMET, ICTUS, NUGENOB-UNAV, PREDIMED-UNAV, RESMENA, NormoP) or Infinium MethylationEPIC Beadchip (OBEKIT).