Fragment screening of FosAKP, room-temperature structure in complex with fragment F2X-entry E12

Fragment screening of FosAKP, room-temperature structure in complex with fragment F2X-entry E12 Descriptor: 6-azanyl-3-methyl-1,3-benzoxazol-2-one, Fosfomycin resistance protein, MANGANESE (II) ION Authors: Guenther, S, Galchenkova, M, Fischer, P, Reinke, P.Y.A, Falke, S, Thekku Veedu, S, Rodrigues, A.C, Senst, J, Meents, A. Deposit date: 2024-07-10 Release date: 2025-07-23 Last modified: 2025-10-22 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Room-temperature X-ray fragment screening with serial crystallography. Nat Commun, 16, 2025针对FosAKP的片段筛选：与片段F2X-entry E12结合的室温复合物结构。配体描述符：6-氨基-3-甲基-1,3-苯并恶唑-2-酮、磷霉素耐药蛋白、锰(II)离子。作者：Guenther, S、Galchenkova, M、Fischer, P、Reinke, P.Y.A、Falke, S、Thekku Veedu, S、Rodrigues, A.C、Senst, J、Meents, A。入库日期：2024-07-10。发布日期：2025-07-23。最后修改日期：2025-10-22。实验方法：X射线衍射（分辨率1.4 Å）。引用文献：采用串行晶体学开展室温X射线片段筛选实验。《自然·通讯》，16卷，2025年。