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Activated CD8+ T cells through NF-κB signaling pathway are instrumental in Behçet’s syndrome

ChEBI2026-07-01 更新2026-07-12 收录

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-17120 数据链接链接失效反馈

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Activated CD8+ T cells through NF-κB signaling pathway are instrumental in Behçet’s syndrome

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2026-07-01

自身免疫疾病机制

细胞表型鉴定

Pathogenic T helper cells (Th cells) that respond to self-antigen cannot be easily distinguished from beneficial Th cells. These cells can generate systemic autoimmune disease in response to widely-ex

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H3K27me3 ChIP-seq of naïve CD4 T cells. H3K27me3 ChIP-seq of naïve CD4 T cells

细胞表观遗传学

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Differentiation and activation of T cells require the activity of numerous histone lysine methyltransferases (HMT) that control the transcriptional T cell output. One of the most potent regulators of

NIAID Data Ecosystem60

Supporting data for "The role of AIM2 inflammasome in Systemic Lupus Erythematosus"

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炎症小体功能

Systemic Lupus Erythematosus is a chronic autoimmune condition in which the body mistakenly attacks itself. It’s aetiopathogenesis is highly complex. Increasing evidence suggests that the innate immun

DataCite Commons2021-09-15 更新50

Interleukin 6 Accelerates Mortality by Promoting the Progression of the Systemic Lupus Erythematosus-Like Disease of BXSB.Yaa Mice

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小鼠疾病模型

IL6 is a multifunctional cytokine that drives terminal B cell differentiation and secretion of immunoglobulins. IL6 also cooperates with IL21 to promote differentiation of CD4+ T follicular helper cel

Figshare2016-04-08 更新60

Genetically-driven target tissue over-expression of CD40: A novel mechanism in autoimmune disease

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免疫病理学

The CD40 gene, an important immune regulatory gene, is also expressed and functional on non-myeloid derived cells, many of which are targets for tissue specific autoimmune diseases, including d thyroi

NIAID Data Ecosystem50

Activated CD8+ T cells through NF-κB signaling pathway are instrumental in Behçet’s syndrome

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