Pluripotent stem cell disease modeling of GATA6 haploinsufficiency in human pancreatic development
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=fd5c9c83b3f25f75b3b915ad49c65e33
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资源简介：
To better understand molecular mechanisms of human pancreatic development associated with GATA6 haploinsufficiency, we performed RNA-seq analysis to characterize the biological processes affected by GATA6 heterozygous mutation.We found majority of top downregulated transcription factors are known to play key roles in pancreatic development and top downregulated genes were enriched with factors involved in developmental processes, with the pancreas being the top affected lineage.
提供机构：
Memorial Sloan Kettering Cancer Center
创建时间：
2022-02-20
