Epigenome wide Association and Stochastic Epigenetic Mutation analysis on 23 twin pairs heterogeneously affected by Congenital Hypothyroidism (CH).

We performed a whole-genome DNA methylation analysis (Infinium HumanMethylation450 BeadChip) on peripheral whole blood of 23 twin pairs (10 monozygotic and 13 dizygotic) heterogeneously (4 concordant and 19 discordant) affected by Congenital Hypothyroidism (CH) at birth. Genome-wide DNA methylation analysis on peripheral whole blood from 23 twin pairs affected by Congenital Hypothyroidism (CH) using Illumina Human Methylation 450K Beadchip.