Glioma-propagating cells as an in vitro screening platform: PLK1 as a case study

ChEBI2012-08-01 更新2026-07-21 收录

胶质瘤靶点筛选

药物筛选模型

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-36782 数据链接链接失效反馈

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Glioma-propagating cells as an in vitro screening platform: PLK1 as a case study

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2012-08-01

RNA-seq of human induced pluripotent stem cells-derived mutant (desmin) and control cardiomyocytes

抗病分子机制

药物筛选模型

Desmin-related diseases are characterized by skeletal muscle weakness, cardiomyopathy, and respiratory dysfunction due to mutations in the desmin gene (DES), which encodes a protein essential for musc

NIAID Data Ecosystem80

Data_Sheet_1_The Histone Deacetylase 9 Stroke-Risk Variant Promotes Apoptosis and Inflammation in a Human iPSC-Derived Smooth Muscle Cells Model.docx

卒中遗传风险机制

药物筛选模型

A common variant in the Histone Deacetylase 9 (HDAC9) gene is the strongest genetic risk for large-vessel stroke, and HDAC9 offers a novel target for therapeutic modulation. However, the mechanisms li

NIAID Data Ecosystem40

Anabolic Factors and Myokines Improve Differentiation of Human Embryonic Stem Cell Derived Skeletal Muscle Cells

骨骼肌细胞分化

药物筛选模型

Skeletal muscle weakness is linked to many adverse health outcomes. Current research to identify new drugs has often been inconclusive due to lack of adequate cellular models. We have previously devel

NIAID Data Ecosystem20

Tet-inducible Keratinocytes as A Novel Tool for Assessment of Anti-TNFα Activities

药物筛选模型

皮肤病研究

Detail method for construction of a Tet-inducible keratinocyte cell model for assessing TNF-α activities is shown in Methods file. Supporting data demonstrating inducible TNF-α in the membrane fracti

NIAID Data Ecosystem50

Impact of Oxygen Tension on the Proteomic Profile of hCMEC/D3 Cells and Implications for Drug Screening

细胞蛋白质组学

药物筛选模型

Untargeted bottom-up proteomic analysis of hCMEC/D3 cells, cultured at 5 kPa and 18 kPa O₂, in the presence and absence of sulforaphane treatment, using an ACQUITY UPLC M-Class system coupled to a SYN

NIAID Data Ecosystem20

Glioma-propagating cells as an in vitro screening platform: PLK1 as a case study

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