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N‑Pyridylimidates as Traceless Acyl Equivalents for Directed C–O Bond Functionalization

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Figshare2022-12-30 更新2026-04-28 收录
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Directing groups are a common strategy to target traditionally inert bonds, with an easily removable directing group being ideal. Herein we disclose our method for rhodium-catalyzed C–O bond functionalization of N-pyridylimidates using a recyclable and traceless amine directing group. In addition to the substrate scope, we discuss the behavior of this class of compounds and how that behavior affects their reactivity.

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2022-12-30
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