Crystal structure of the human c5a in complex with MEDI7814 a neutralising antibody
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Crystal structure of the human c5a in complex with MEDI7814 a neutralising antibody Descriptor: COMPLEMENT C5, MEDI7814, SULFATE ION Authors: Colley, C, Sridharan, S, Dobson, C, Popovic, B, Debreczeni, J.E, Hargreaves, D, Edwards, B, Brennan, J, England, L, Fung, S, An Eghobamien, L, Sivars, U, Woods, R, Flavell, L, Renshaw, G.J, Wickson, K, Wilkinson, T, Davies, R, Bonnell, J, Warrener, P, Howes, R, Vaughan, T. Deposit date: 2014-07-25 Release date: 2015-08-12 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors. MAbs, 10, 2018
人类补体C5a与中和性抗体(neutralising antibody)MEDI7814复合物的晶体结构
描述项:补体C5(COMPLEMENT C5)、MEDI7814、硫酸根离子(SULFATE ION)
作者:Colley, C、Sridharan, S、Dobson, C、Popovic, B、Debreczeni, J.E、Hargreaves, D、Edwards, B、Brennan, J、England, L、Fung, S、An Eghobamien, L、Sivars, U、Woods, R、Flavell, L、Renshaw, G.J、Wickson, K、Wilkinson, T、Davies, R、Bonnell, J、Warrener, P、Howes, R、Vaughan, T
提交日期:2014年7月25日
发布日期:2015年8月12日
最后修改日期:2024年10月16日
实验方法:X射线衍射(X-RAY DIFFRACTION,分辨率2.12埃)
引用文献:《一种可阻断与C5aR1及C5aR2受体结合的高亲和力C5a单克隆抗体(monoclonal antibody)的结构与表征》,《单克隆抗体(MAbs)》,第10卷,2018年
创建时间:
2014-07-25



