Data from: Excitation-contraction coupling, cardiomyocyte electrophysiology, and transcriptome profiles in two HFpEF murine models: Etiology and sex-dependent differences

This dataset contains the source data supporting the article entitled
Excitation-contraction coupling, cardiomyocyte electrophysiology, and
transcriptome profiles in two HFpEF murine models: Etiology and
sex-dependent differences. The dataset supports key findings in recent
two-hit translational animal models of heart failure with preserved
ejection fraction (HFpEF), including the hypertensive,
nitrosative-stressed mice fed with high-fat diet and L-NAME (HFD+L-NAME)
and the obese-diabetic leptin receptor-deficient db/db mice with excess
aldosterone (db/db+Aldo), which may phenocopy select subgroups of HFpEF.
Morphometry, echocardiography, electrophysiology (action potentials and
ionic currents), fluorescent Ca imaging, and RNA sequencing data are
included in separate Excel sheets with individual cell data and group
statistics. The dataset is structured to follow the sequence of data
presented in the Figures in the article and to ease the navigation between
the uploaded data files.