Sample Size and Research Cost for Different Booster Vaccine Efficacy Values.
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Length of follow-up 2 years. assumed active TB risk = 2% in control arm; lower limit confidence interval set to >30%; Power 90%; Significance level = .05.†The estimated cost of Phase IIB (clinical trials plus start-up costs), added to the cost of Phase III trials to give a final research and development cost.
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2015-12-02



