Characterization of mature IL18R- and IL18R+ Tregs in the thymus

Using Foxp3.RFP Rag.GFP reporter mice, we characterized differences between the IL18R- and the IL18R+ mature Treg populations in the thymus mRNA profiles of different Treg populations of the thymus was generated by MARSeq Method. These include: Rag.GFP+(recently developed) Tregs, Rag.GFP- (mature)IL18R- Tregs and Rag.GFP- (mature)IL18R+ Tregs