Association of LEDGF/p75 protein expression in colon, liver, prostate, thyroid and uterine tumors with patients' clinical characteristics.

Bold numbers denote significant P values. P values for the association of immunohistochemical LEDGF/p75 expression (high vs. low comparison) in tumors with patients' age and sex were calculated using Fisher's exact test, while those for tumor stage were calculated using Kendall's tau b correlation analysis. At the time of surgical excision of the tissues, the median age of donors was 62 years for colon cancer, 53 years for liver cancer, 66 years for prostate cancer, 48 years for thyroid cancer, and 70 years for uterine cancer. The tumor stages (pT1 to pT4) correspond to pathologic tumor stages T1 through T4 used in the TNM system of cancer staging. The TNM system is based on the extent of the tumor (T), the extent of spread to the lymph nodes (N), and the presence of distant metastasis (M). A number is added to each letter (eg. T1, T2, T3, T4) to indicate the size or extent of the primary tumor and the extent of cancer spread. N/A, Not applicable; N/D, No data available.