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Physical mapping, cloning, and identification of genes within a 500-kb region containing BRCA1.

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PubMed Central1995-05-09 更新2026-05-02 收录
下载链接:
https://pmc.ncbi.nlm.nih.gov/articles/PMC41944/
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资源简介:
BRCA1 is a breast/ovarian cancer susceptibility gene on human chromosome 17q21. We describe a complete and detailed physical map of a 500-kb region of genomic DNA containing the BRCA1 gene and the partial cloning in phage P1 artificial chromosomes. Approximately 70 exons were isolated from this region, 11 of which were components of the BRCA1 gene. Analysis of the other exons revealed a rho-related G protein and the interferon-induced leucine-zipper protein IFP-35. IMAGES:
提供机构:
National Academy of Sciences
创建时间:
1995-05-09
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