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ATAC-Seq examining the TFH and TEFF primed in Wild-type and IL6 KO mice

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE124588
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The goal of this study was to determine if there were differences in chromatin accessiblity between TFH and TEFF developing in Wild-type and IL6 KO mice OTII (CD45.1+) cells were adoptively transferred into WT (C57Bl/6) and Il6-/- recipient mice. One day later, recipient mice were infected with PR8-OTII. Seven days after infection, 30,000 donor-derived CD45.1+CXCR5hiSLAMloCD4+CD19- TFH and CD45.1+CXCR5loSLAMhi CD4+CD19- Teff cells were sorted from the mLN of WT and Il6-/- recipient mice
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2019-10-16
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