Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with ASAP-0037711-001 (A71EV2A-x4977)

Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with ASAP-0037711-001 (A71EV2A-x4977) Descriptor: (3S)-N~1~-[6-(methylsulfanyl)quinolin-5-yl]piperidine-1,3-dicarboxamide, DIMETHYL SULFOXIDE, Protease 2A, ... Authors: Lithgo, R.M, Fairhead, M, Koekemoer, L, Balcomb, B.H, Capkin, E, Chandran, A.V, Golding, M, Godoy, A.S, Aschenbrenner, J.C, Marples, P.G, Ni, X, Thompson, W, Tomlinson, C.W.E, Wild, C, Winokan, M, Xavier, M.-A.E, Kenton, N, Tucker, J, DiPoto, M, Lee, A, Fearon, D, von Delft, F. Deposit date: 2025-03-12 Release date: 2025-04-02 Last modified: 2025-04-09 Method: X-RAY DIFFRACTION (1.511 Å) Cite: Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre To Be Published

本数据集为来自ASAP AViDD中心的抑制剂复合物形式的柯萨奇病毒A16（Coxsackievirus A16）G-10株2A蛋白酶（2A protease）的集群提交数据——具体为柯萨奇病毒A16（Coxsackievirus A16）G-10株2A蛋白酶与ASAP-0037711-001（A71EV2A-x4977）结合的晶体结构（crystal structure）。
描述项：(3S)-N¹-[6-(甲硫基)喹啉-5-基]哌啶-1,3-二甲酰胺、二甲基亚砜（DIMETHYL SULFOXIDE）、2A蛋白酶等。
作者：Lithgo, R.M、Fairhead, M、Koekemoer, L、Balcomb, B.H、Capkin, E、Chandran, A.V、Golding, M、Godoy, A.S、Aschenbrenner, J.C、Marples, P.G、Ni, X、Thompson, W、Tomlinson, C.W.E、Wild, C、Winokan, M、Xavier, M.-A.E、Kenton, N、Tucker, J、DiPoto, M、Lee, A、Fearon, D、von Delft, F.
提交日期：2025-03-12
发布日期：2025-04-02
最后修改日期：2025-04-09
实验方法：X射线衍射（X-RAY DIFFRACTION），衍射波长1.511埃。
引用：柯萨奇病毒A16（G-10）2A蛋白酶与ASAP AViDD中心来源抑制剂复合物的集群提交数据，待发表。