INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z1593306637

INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z1593306637 Descriptor: DIMETHYL SULFOXIDE, N-(4-chlorophenyl)-N'-[(2R)-1-hydroxybutan-2-yl]urea, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Authors: Bradshaw, W.J, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024

INPP5D PanDDA分析组提交——SHIP1的磷酸酶结构域与C2结构域结合Z1593306637的复合物晶体结构。描述：二甲基亚砜（DIMETHYL SULFOXIDE）、N-(4-氯苯基)-N'-[(2R)-1-羟基丁-2-基]脲、磷脂酰肌醇3,4,5-三磷酸5-磷酸酶1（Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1）。作者：Bradshaw, W.J.、Newman, J.A.、von Delft, F.、Arrowsmith, C.H.、Edwards, A.M.、Bountra, C.、Gileadi, O.。提交日期：2020-10-30，发布日期：2020-11-11，最后修改日期：2026-02-18。实验方法：X射线衍射（X-RAY DIFFRACTION）（分辨率1.35埃）。引用：《SHIP1与SHIP2的C2结构域对肌醇5-磷酸酶活性的调控》，《Structure》，2024年。