Hypertrophic cardiomyopathy (HCM) causes sudden cardiac death (SCD) due to ventricular arrhythmias (VA) manifesting from myocardial fibrosis proliferation. Current clinical risk stratification criteri
Additional image data supporting the manuscript: VT/VF risk in animal model of hypertensive heart disease predicted by distribution of patchy fibrosis.
Additional image data supporting the manuscript: VT/VF risk in animal model of hypertensive heart disease predicted by distribution of patchy fibrosis.
The International Council on Harmonization (ICH) S7B and E14 regulatory guidelines are sensitive but not specific for predicting which drugs are pro‐arrhythmic. In response, the Comprehensive In Vitro