Structure of the signal-regulatory protein (SIRP) alpha domain that binds CD47.

Structure of the signal-regulatory protein (SIRP) alpha domain that binds CD47. Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 Authors: Hatherley, D, Harlos, K, Dunlop, D.C, Stuart, D.I, Barclay, A.N. Deposit date: 2007-03-08 Release date: 2007-03-27 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The Structure of the Macrophage Signal Regulatory Protein Alpha (Sirpalpha) Inhibitory Receptor Reveals a Binding Face Reminiscent of that Used by T Cell Receptors. J.Biol.Chem., 282, 2007

结合CD47的信号调节蛋白α（signal-regulatory protein α, SIRPα）结构域的晶体结构。样品组分：2-(N-吗啉代)乙磺酸（2-(N-MORPHOLINO)-ETHANESULFONIC ACID）、硫酸根离子、非受体型蛋白酪氨酸磷酸酶底物1（TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1）。作者：Hatherley, D、Harlos, K、Dunlop, D.C、Stuart, D.I、Barclay, A.N。提交日期：2007-03-08；发布日期：2007-03-27；末次修改日期：2024-11-06。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.8埃（Å）。引用文献：《巨噬细胞信号调节蛋白α（SIRPα）抑制性受体的结构揭示出与T细胞受体相似的结合界面》，《生物化学杂志（J. Biol. Chem.）》，第282卷，2007年。