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Ultra-Rare Quartet Fracture Class, Unique Reference-Backed Displaced Appendage, and Gate-Specific Rescue Vector in a Computational Longevity Discovery Pipeline (Trinity Claims #60-#62, 2026-03-19)

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Zenodo2026-03-19 更新2026-05-26 收录
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This version fixes three connected computational biology results from the Trinity longevity-discovery pipeline. Claim #60 shows that the strong-core plus partial-plus-veto outsider geometry is an ultra-rare quartet fracture class in the evaluable huMAP3 quartet universe. Claim #61 shows that only one of those rare fractures is reference-backed by both an exact same-core triad and a stable same-core replacement quartet: the TOP3A/RMI2/CCDC69/PITRM1 scaffold, with RMI1 as the stable replacement outsider. Claim #62 shows that the fixed-core PITRM1 to RMI1 swap acts as a gate-specific rescue vector concentrated on the RMI2 side of the same core. This version also includes differential falsification and readout-priority sheets for wet-lab follow-up. This is a computational discovery package and not a completed causal validation study.

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Zenodo
创建时间:
2026-03-19
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