Ntrk2 activates Ras signaling through Shc1

In rat neurons, Shc1-mediated recruitment of the Grb2:Sos1 complex to the activated Ntrk2 (TrkB) receptor leads to activation of Ras (Chan et al. 2001).

在哺乳动物神经元中，Shc1介导的Grb2:Sos1复合物募集至激活的Ntrk2（TrkB）受体，进而导致Ras（Chan等，2001年）的激活。