Setdb1-loss induces type-I interferons and immune clearance of melanoma
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2023-12-31
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Additional file 3 of Transcriptional dynamics of transposable elements in the type I IFN response in Myotis lucifugus cells
Additional file 3: Table S2. RNAseq 24hrs Contrast IFNvsUN.
DataCite Commons2022-09-07 更新90
Mars2 deficiency in mouse leads to activation of the type I interferon response
Recessive single-nucleotide mutations in MARS2 are causative for a mitochondrial translation deficiency disorder with a primary phenotype including developmental delay, sensorineural hearing loss, and
NIAID Data Ecosystem50
Gene expression profiles in HMC3 cells after exposure to ketamine or its active metabolites: 2R6R-HNK and 2S6S-HNK
This study was designed to clarify mechanisms of action for ketamine and its active metabolites, (2R,6R;2S,6S)-hydroxynorketamine (HNK), which also appear to play a major role in ketamine's rapid anti
NIAID Data Ecosystem30
The Type I interferon response impairs differentiation potential of pluripotent stem cells [RT-qPCR]. The Type I interferon response impairs differentiation potential of pluripotent stem cells [RT-qPCR]
Upon virus infection,pluripotent stem cells neither induce nor respond to canonical Type I interferons (IFN-I). To better understand this biology,we characterized induced pluripotent stem cells (iPSCs
NIAID Data Ecosystem70
Induction of Noxa-Mediated Apoptosis by Modified Vaccinia Virus Ankara Depends on Viral Recognition by Cytosolic Helicases, Leading to IRF-3/IFN-β-Dependent Induction of Pro-Apoptotic Noxa
Viral infection is a stimulus for apoptosis, and in order to sustain viral replication many viruses are known to carry genes encoding apoptosis inhibitors. F1L, encoded by the orthopoxvirus modified v
NIAID Data Ecosystem50
