Effect of mutant GNAS expression in the doxycycline-inducible Kras;Gnas mouse model of IPMN using scRNA-seq
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https://www.ncbi.nlm.nih.gov/sra/SRP527918
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资源简介：
We investigated the effect of GNAS(R201C) expression in the Kras;Gnas model of pancreatic intraductal papillary mucinous neoplasms where transgenic mutant GNAS is doxycycline inducible (LGKC; p48(Cre), Kras(LSL-G12D), Rosa26(LSL-rtTA)), Tg(TetO-GNAS(R201C)) using scRNA-seq of dissociated pancreatic tissues. Overall design: Four Kras;Gnas mice were fed with doxycycline or normal lab feed for 10 weeks starting at 8 weeks of age (2 mice per group). Pancreata were dissociated and subjected to scRNA-seq.
创建时间：
2024-09-17
