N-acetyltransferase 10 drives cisplatin chemoresistance by enhancing ac4C-associated DNA repair in bladder cancer
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https://www.ncbi.nlm.nih.gov/sra/SRP367833
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资源简介：
To explore the molecular mechanism underlying NAT10-mediated cisplatin resistance in bladdder cancer, a genome-wide RNA-sequencing was conducted to compare gene expression profiles of T24 and UM-UC-3 cells with NAT10 knockdown and control. And acRIP-seq was performed to identified the downstream targets of NAT10. Overall design: Detection of acetylated cytide in RNA with ac4C-immunoprecipitation (acRIP), along with RNA-seq after bladder cancer cell line T24 and UM-UC-3 were transfected with the NAT10 siRNA or control for 48h.
创建时间：
2023-03-03
