官方服务：
资源简介：
A herg blocker/non-blocker dataset
应用场景：
创建时间：
2022-03-20
相关数据集
Inhibition of PRKAA/AMPK (Ser485/491) phosphorylation by crizotinib induces cardiotoxicity via perturbing autophagosome-lysosome fusion
Crizotinib, a small-molecule tyrosine kinase inhibitor targeting ALK, MET and ROS1, is the first-line drug for ALK-positive metastatic non-small cell lung cancer and is associated with severe, sometim
DataCite Commons2024-02-07 更新60
hERG Inhibition Data on Novel NL-Compounds
Compound 1 is NL221-75 Compound 2 is NL33-104 Compound 3 is NL34-113 Compound 4 is NL350-02
NIAID Data Ecosystem50
SFN administered during DOX-treatment improves ETC function in non-tumor bearing animals.
Respiration status of complex I, II+III, and IV of the ETC was evaluated in fresh left ventricular tissue as described in the Materials and Methods. According to oxygen flux measures (pmol/mg/substrat
NIAID Data Ecosystem70
Structure-Based Prediction of hERG-Related Cardiotoxicity: A Benchmark Study
Drug-induced blockade of the human ether-à-go-go-related gene (hERG) channel is today considered the main cause of cardiotoxicity in postmarketing surveillance. Hence, several ligand-based approaches
NIAID Data Ecosystem60
