Cancer incidence and cancer mortality in all 27 trials, by site.

Excluding death from cancers known to have been first diagnosed prior to randomisation. ICD-9 cancer codes: Gastrointestinal (140–159); Lip, mouth or pharynx (140–149); Oesophageal (150); Stomach (151); Large bowel or intestine (152–154); Liver (155); Gall bladder or bile-ducts (156); Pancreas (157); Other gastrointestinal (158,159); Genitourinary (179–189); Prostate (185); Penis/Scrotum (187); Uterus (179,180,182); Ovarian (183); Other genitourinary (181,184,186); Bladder (188); Kidney (189); Respiratory (160–163,165); Trachea/Lung (162); Other respiratory (160,161,163,165); Female breast (174); Haematological (200–208); Melanoma (172); Other/unspecified ([Neurological (191,192); Other known site (164,170,171,175,176,190,193–195); Unspecified (196–199, 209)]); All cancer (140–209 excluding 173). If the ICD9 cause of death was 173 or 210–239 then both cancer incidence and cancer death was coded as unknown cancer. P-values are continuity corrected.